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Technical Information   Posters   Papers

Application #:
TI0A79
Type:
Application Note
Categories:
DNA Related Compounds
LC-MS
Compounds:
5'-GTTTTCCCAGTCACGACGTT-3'
5'-GGAAACAGCTATGACCATGA-3'
Column(s):
Unison UK-C18 (50 x 3.0mm)

LC-MS: Deoxyoligonucleotides

Application #:
TI0A78
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
ivermectin
Column(s):
Unison UK-C18 (50 x 3.0mm)
Unison UK-C8 (50 x 3.0mm)
Unison UK-Phenyl (50 x 3.0mm)
Unison UK-C1 (50 x 3.0mm)

LC-MS: Ivermectin (antiparasitic drug)

Application #:
TI0A77
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
ivermectin
Column(s):
Cadenza CD-C18 (50 x 3.0mm)
Cadenza CW-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)

LC-MS: Ivermectin (antiparasitic drug)

Application #:
TI0A51
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
tipepidine
hibenzic acid
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Cadenza CX-C18 (75 x 4.6mm)

Tipepidine hibenzate (Antitussive, Expectorant)

Application #:
TI0A50
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
tipepidine
hibenzic acid
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-C1 (75 x 4.6mm)

Tipepidine hibenzate (Antitussive, Expectorant)

Application #:
TI0A48
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
omarigliptin
Column(s):
Cadenza CD-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)
Cadenza CX-C18 (50 x 3.0mm)

LC-MS: Omarigliptin (Oral antidiabetic drug)

Application #:
TI0A44
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
etodolac
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Cadenza CX-C18 (75 x 4.6mm)

Etodolac (nonsteroidal anti-inflammatory drug, NSAIDs)

Application #:
TI0A43
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
etodolac
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-C1 (75 x 4.6mm)

Etodolac (nonsteroidal anti-inflammatory drug, NSAIDs)

Application #:
TI0A42
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
propiverine
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Cadenza CX-C18 (75 x 4.6mm)

Propiverine (Anticholinergic, Ca-antagonist, Antimuscarinic)

Application #:
TI0A41
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
propiverine
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-C1 (75 x 4.6mm)

Propiverine (Anticholinergic, Ca-antagonist, Antimuscarinic)

Application #:
TI0A40
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
rizatriptan
benzoic acid
Column(s):
Unison UK-C18 (50 x 3.0mm)
Unison UK-C8 (50 x 3.0mm)
Unison UK-C1 (50 x 3.0mm)

Rizatriptan benzoate (treatment of migraine headaches)

Application #:
TI0A39
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
levofloxacin
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-C1 (75 x 4.6mm)

Levofloxacin (new quinolone, antibiotics)

Application #:
TI0A38
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
levofloxacin
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Cadenza CX-C18 (75 x 4.6mm)

Levofloxacin (new quinolone, antibiotics)

Application #:
TI0A36
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
eperisone
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C1 (75 x 4.6mm)

Eperisone (antispasmodic)

Application #:
TI0A31
Type:
Application Note
Categories:
Column Performance
Food Chemistry
Vitamins
LC-MS
Compounds:
eicosapentaenoic acid (EPA)
docosahexaenoic acid (DHA)
arachidonic acid (AA)
Column(s):
Cadenza CD-C18 (50 x 2.0mm)
Cadenza CW-C18 (50 x 2.0mm)
Unison UK-C18 (50 x 2.0mm)
Cadenza CX-C18 (50 x 2.0mm)

LC-MS: Omega-3 and Omega-6 fatty acids

Application #:
TI0A30
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
vancomycin
Column(s):
Cadenza CD-C18 (150 x 4.6mm)
Cadenza CL-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)

Antibiotic (vancomycin)

Application #:
TI0A28
Type:
Application Note
Categories:
Column Performance
Food Chemistry
Vitamins
LC-MS
Compounds:
ethyl eicosapentaenoate (Ethyl-EPA)
ethyl docosahexaenoate (Ethyl-DHA)
Column(s):
Cadenza CD-C18 (50 x 2.0mm)
Cadenza CW-C18 (50 x 2.0mm)
Unison UK-C18 (50 x 2.0mm)
Unison UK-C8 (50 x 2.0mm)
Unison UK-Phenyl (50 x 2.0mm)
Cadenza CX-C18 (50 x 2.0mm)

LC-MS: Omega-3 fatty acid ethyl esters

Application #:
TI0A27
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
tizanidine
Column(s):
Cadenza CD-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)
Unison UK-C1 (50 x 3.0mm)

Tizanidine (muscle-relaxant) impurity

Application #:
TI0A26
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
tizanidine
Column(s):
Cadenza CD-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)
Unison UK-C1 (50 x 3.0mm)

Tizanidine (muscle-relaxant)

Application #:
TI0A23
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
varenicline tartrate
Column(s):
Cadenza CD-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)

LC-MS: Varenicline (Smoking cessation adjuvant)

Application #:
TI0A22
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
tadalafil
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)
Cadenza CX-C18 (75 x 4.6mm)

Tadalafil (phosphodiesterase type 5 inhibitor, PDE5I)

Application #:
TI0A20
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
eperisone
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Eperisone (antispasmodic)

Application #:
TI0A19
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
eperisone
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Cadenza CX-C18 (75 x 4.6mm)

Eperisone (antispasmodic)

Application #:
TI0A15
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
ractopamine hydrochloride
Column(s):
Cadenza CD-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)
Cadenza CX-C18 (150 x 4.6mm)

LC-MS: Ractopamine (veterinary drug)

Application #:
TI0992
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Botanicals
LC-MS
Compounds:
scopolamine
physostigmine
atropine
Column(s):
Cadenza CD-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Cadenza CX-C18 (150 x 3.0mm)

LC-MS: Alkaloids

Application #:
TI0991
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Industrial Chemical
Compounds:
sodium heptylsulfonate
sodium octylsulfonate
sodium dodecylsulfate
Column(s):
Cadenza CD-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Cadenza CX-C18 (150 x 3.0mm)

Sodium alkyl sulfates (SAS)

Application #:
TI0990
Type:
Application Note
Categories:
Column Performance
Industrial Chemical
Environmental and Agricultural
LC-MS
Compounds:
perfluorobutanesulfonic acid (PFBS)
perfluorooctanoic acid (PFOA)
perfluorooctanesulfonic acid (PFOS)
Column(s):
Unison UK-C18 (150 x 3.0mm)
Cadenza CX-C18 (150 x 3.0mm)

LC-MS: Perfluoroalkyl acids (PFAA)

Application #:
TI0989
Type:
Application Note
Categories:
Column Performance
Industrial Chemical
LC-MS
Compounds:
cyclohexylamine
1-hexylamine
1-octylamine
1-octadecylamine
Column(s):
Unison UK-C18 (150 x 3.0mm)
Cadenza CX-C18 (150 x 3.0mm)

LC-MS: Aliphatic amines

Application #:
TI0984
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
clorpheniramine
dextromethorphan
propylparaben
Column(s):
Unison UK-C18 (150 x 3.0mm)
Cadenza CX-C18 (150 x 3.0mm)

Cold medicine compounds

Application #:
TI0982
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
N-acetyl-4-benzoquinone imine
acetaminophen
Column(s):
Unison UK-C18 (150 x 3.0mm)
Cadenza CX-C18 (150 x 3.0mm)

Acetaminophen and metabolite

Application #:
TI0981
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
doxepin (e-isomer)
doxepin (z-isomer)
Column(s):
Unison UK-C18 (150 x 3.0mm)
Cadenza CX-C18 (150 x 3.0mm)

Doxepin isomers

Application #:
TI0980
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
trans-doxepin
cis-doxepin
Column(s):
Unison UK-C18 (250 x 3.0mm)
Cadenza CX-C18 (250 x 3.0mm)

LC-MS: Doxepin isomers

Application #:
TI0978
Type:
Application Note
Categories:
Column Performance
Industrial Chemical
Environmental and Agricultural
Compounds:
o-terphenyl
triphenylene
Column(s):
Cadenza CD-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Cadenza CX-C18 (150 x 3.0mm)

Steric selectivity

Application #:
TI0975
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Food Chemistry
Compounds:
methylparaben
ethylparaben
isopropylparaben
propylparaben
isobutylparaben
butylparaben
Column(s):
Cadenza CD-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Cadenza CX-C18 (150 x 3.0mm)

Paraben isomers

Application #:
TI0953
Type:
Application Note
Categories:
Column Performance
LC-MS
Biochemistry/Metabolism
Compounds:
ATP
GTP
UTP
CTP
TTP
Column(s):
Unison UK-C18 (150 x 2.0mm)

Metal Free Column: Nucleoside triphosphate (NTP), Trinucleotide

Application #:
TI0930
Type:
Application Note
Categories:
LC-MS
Pharmaceuticals and Cosmetics
Column Performance
Compounds:
bifenthrin
etoxazole
fipronil
pridaben
Column(s):
Cadenza CD-C18 (50 x 2.0mm)
Unison UK-C18 (50 x 2.0mm)

LC-MS/MS: Insecticides

Application #:
TI0928
Type:
Application Note
Categories:
LC-MS
Pharmaceuticals and Cosmetics
Column Performance
Compounds:
Fipronil
Column(s):
Cadenza CD-C18 (50 x 2.0mm)
Unison UK-C18 (50 x 2.0mm)

LC-MS/MS: Insecticide (Fipronil)

Application #:
TI0879
Type:
Application Note
Categories:
LC-MS
Food Chemistry
Botanicals
Amino Acids and Peptides
Column Performance
Compounds:
Allicin
diallyl disulfide
Column(s):
Cadenza CD-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)

Allicin and diallyl disulfide in Garlic

Application #:
TI0862
Type:
Application Note
Categories:
LC-MS
Food Chemistry
Compounds:
taxifolin
myricetin
quercetin
kaempferol
apigenin
baicalein
chrysin
acacetin
Column(s):
Unison UK-C18 (100 x 3.0mm)
Unison UK-C8 (100 x 3.0mm)

LC-MS: Flavonoids

Application #:
TI0861
Type:
Application Note
Categories:
LC-MS
Food Chemistry
Compounds:
taxifolin
myricetin
quercetin
kaempferol
apigenin
baicalein
chrysin
acacetin
Column(s):
Unison UK-C18 (100 x 3.0mm)

LC-MS: Flavonoids

Application #:
TI0860
Type:
Application Note
Categories:
LC-MS
Food Chemistry
Compounds:
taxifolin
myricetin
quercetin
kaempferol
apigenin
baicalein
chrysin
acacetin
Column(s):
Cadenza CD-C18 (100 x 3.0mm)
Unison UK-C18 (100 x 3.0mm)

LC-MS: Flavonoids

Application #:
TI0854
Type:
Application Note
Categories:
LC-MS
Biochemistry/Metabolism
Column Performance
Compounds:
triiodothyronine (T3)(L-3,3',5-triiodothyronine)
thyroxine (T4)(L-3,5,3',5'-tetraiodothyronine)
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Cadenza CW-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)
Unison UK-C8 (50 x 3.0mm)
Unison UK-Phenyl (50 x 3.0mm)

LC-MS: Thyroid hormone

Application #:
TI0848
Type:
Application Note
Categories:
LC-MS
Biochemistry/Metabolism
Amino Acids and Peptides
Compounds:
orexin A
orexin B
Column(s):
Intrada WP-RP (100 x 3.0mm)
Cadenza CD-C18 (100 x 3.0mm)
Cadenza CW-C18 (100 x 3.0mm)
Cadenza CL-C18 (100 x 3.0mm)
Unison UK-C18 (100 x 3.0mm)
Unison UK-C8 (100 x 3.0mm)
Unison UK-Phenyl (100 x 3.0mm)
Dacapo DX-C18 (100 x 3.0mm)

LC-MS: Orexin A and B

Application #:
TI0842
Type:
Application Note
Categories:
LC-MS
Pharmaceuticals and Cosmetics
Compounds:
doxylamine
risperidone
olanzapine
Column(s):
Unison UK-C18 (100 x 3.0mm)
Unison UK-C8 (100 x 3.0mm)
Unison UK-Phenyl (100 x 3.0mm)

LC-MS: Antipsychotics

Application #:
TI0838
Type:
Application Note
Categories:
LC-MS
Pharmaceuticals and Cosmetics
Compounds:
vancomycin
Column(s):
Unison UK-C18 (50 x 4.6mm)

Antibiotic (vancomycin)

Application #:
TI0836
Type:
Application Note
Categories:
LC-MS
Pharmaceuticals and Cosmetics
Compounds:
sumatriptan
zolmitriptan
eletriptan
Column(s):
Unison UK-C18 (100 x 3.0mm)
Unison UK-Phenyl (100 x 3.0mm)

LC-MS: antimigraines (selective serotonin agonists)

Application #:
TI0835
Type:
Application Note
Categories:
LC-MS
Pharmaceuticals and Cosmetics
Compounds:
sumatriptan
zolmitriptan
eletriptan
Column(s):
Unison UK-C18 (100 x 3.0mm)
Unison UK-Phenyl (100 x 3.0mm)

LC-MS: antimigraines (selective serotonin agonists)

Application #:
TI0809
Type:
Application Note
Categories:
LC-MS
Environmental and Agricultural
Compounds:
thiabendazole
imazalil
o-phenylphenol
prochloraz
Column(s):
Unison UK-C18 (50 x 3.0mm)
Unison UK-C8 (50 x 3.0mm)
Unison UK-Phenyl (50 x 3.0mm)

LC-MS: Fungicides for citrus fruits

Application #:
TI0802
Type:
Application Note
Categories:
LC-MS
Biochemistry/Metabolism
Compounds:
L-vanillylmandelic acid (VMA)
L-mandelic acid (MA)
homovanillic acid (HVA)
Column(s):
Unison UK-C18 (50 x 3.0mm)
Unison UK-Phenyl (50 x 3.0mm)

LC-MS: Neuroblastoma related compounds

Application #:
TI0731
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
shikimic acid
L-tyrosine
L-phenylalanine
L-tryptophan
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

The Scherzo SS-C18 column provides better retention of Shikimic Acid than a standard C18 column.

Application #:
TI0730
Type:
Application Note
Categories:
Industrial Chemical
Compounds:
sodium alkylbenzenesulfonates (including branched structure)
Column(s):
Unison UK-C18 (150 x 3.0mm)
Unison UK-Phenyl (150 x 3.0mm)

The Unison UK-Phenyl column separates surfactants of different lengths better than a standard C18 column.

Application #:
TI0727
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
Coenzyme A (CoA)
acetyl coenzyme (Acetyl-CoA)
Column(s):
Cadenza CW-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Unison UK-C8 (150 x 3.0mm)

Cadenza CW-C18, Unison UK-C18, and Unison UK-C8 are all able to resolve the very polar and charged Acetyl CoA and CoA, differing only in an acetyl group.

Application #:
TI0725
Type:
Application Note
Categories:
Amino Acids and Peptides
Biochemistry/Metabolism
Compounds:
angiotensin II (human)
angiotensin IV (human)
[val5]-angiotensin I (bovine)
angiotensin I (human)
angiotensin III (human)
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Oligopeptides (angiotensins)

Application #:
TI0724
Type:
Application Note
Categories:
Amino Acids and Peptides
Compounds:
angiotensin II (human)
angiotensin IV (human
[val5]-angiotensin I (bovine)
angiotensin I (human)
angiotensin II (human)
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Oligopeptides (angiotensins)

Application #:
TI0720
Type:
Application Note
Categories:
Biochemistry/Metabolism
Botanicals
Compounds:
Shikimic acid
malic acid
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

The Scherzo SM-C18 and Scherzo SS-C18 column resolve very polar carboxylic acids that normally co-elute on a standard C18 column (Unison UK-C18).

Application #:
TI0718
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
Prostaglandin F2
Prostaglandin E2
Column(s):
Cadenza CD-C18 (150 x 3.0mm)
Cadenza CW-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Unison UK-C8 (150 x 3.0mm)
Unison UK-Phenyl (150 x 3.0mm)

Under neutral pH conditions, columns in the Unison and Cadenza series have similar retention and resolution properties.

Application #:
TI0717
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
Prostaglandin F2
Prostaglandin E2
Column(s):
Cadenza CD-C18 (150 x 3.0mm)
Cadenza CW-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Unison UK-C8 (150 x 3.0mm)
Unison UK-Phenyl (150 x 3.0mm)

Under acidic pH conditions, columns in the Unison and Cadenza series have similar retention and resolution properties.

Application #:
TI0716
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
Prostaglandin F2
Prostaglandin E2
Column(s):
Unison UK-C18 (150 x 3.0mm)

On the Unison UK-C18 column, tetrahydrofuran gives better resolution of Prostaglandins than acetonitrile and acetone.

Application #:
TI0715
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
Prostaglandin F2
Prostaglandin E2
Column(s):
Unison UK-C18 (150 x 3.0mm)

Acetonitrile and methanol have opposite retention properties in the separation of prostaglandins on the Unison UK-C18 column.

Application #:
TI0714
Type:
Application Note
Categories:
Botanicals
Food Chemistry
Compounds:
inositol hexaphosphate (phytic acid )
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)

The Scherzo SM-C18 column is able to retain a highly polar compound (multiple phosphate groups) better than a standard C18 column.

Application #:
TI0706
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
Tadalafil
Sildenafil and Vardenafil
Column(s):
Unison UK-C18 (75 x 2.0mm)

Tadalafil, Sildenafil, and Vardenafil are all polar small molecules that are easily separated on the Unison UK-C18 HT column. Not only are the slight structural differences between Sildenafil and Vardenafil recognized by the column, but it also separates all three compounds within 1.5 minutes.

Application #:
TI0705
Type:
Application Note
Categories:
Botanicals
Compounds:
tannic acid
Column(s):
Cadenza CD-C18 (250 x 4.6mm)
Cadenza CW-C18 (250 x 4.6mm)
Cadenza CL-C18 (250 x 4.6mm)
Unison UK-C18 (250 x 4.6mm)

Tannic acid

Application #:
TI0704
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
Spermine and spermidine
Column(s):
Scherzo SM-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)

The Scherzo SM-C18 column can separate these two molecules, which would normally coelute on a standard C18 column.

Application #:
TI0703
Type:
Application Note
Categories:
Industrial Chemical
Compounds:
Formic acid and acetic acid
Column(s):
Scherzo SW-C18 (250 x 3.0mm)
Scherzo SM-C18 (250 x 3.0mm)
Scherzo SS-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

The Scherzo SM-C18 and SS-C18 show excellent resolution of these small molecules, which normally coelute on a standard C18 column.

Application #:
TI0702
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
Arsenobetaine
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

The Scherzo SS-C18 column shows improved resolution of arsenobetaine compared to a standard C18 column. The Scherzo SM-C18 and the Scherzo SW-C18 show similar retention of this zwitterion as the standard Unison UK-C18 column.

Application #:
TI0701
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Botanicals
Biochemistry/Metabolism
Compounds:
Allantoin
allantoic acid and uric acid
Column(s):
Scherzo SW-C18 (250 x 3.0mm)
Scherzo SM-C18 (250 x 3.0mm)
Scherzo SS-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

The Scherzo SM-C18 and the Scherzo SW-C18 show similar retention of these small molecules as the standard Unison UK-C18. However, the Scherzo SS-C18 shows the best resolution between these three compounds.

Application #:
TI0700
Type:
Application Note
Categories:
Saccharides
Amino Acids and Peptides
Compounds:
Sialylglycopeptide
Column(s):
Scherzo SW-C18 (250 x 3.0mm)
Scherzo SM-C18 (250 x 3.0mm)
Scherzo SS-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

The Scherzo family columns can separate this glycopeptide with varying retention. The Scherzo SW-C18 has the least retention, followed by the Scherzo SM-C18, followed by the Scherzo SS-C18 which has the most retention.

Application #:
TI0699
Type:
Application Note
Categories:
Saccharides
Amino Acids and Peptides
Compounds:
Sialylglycopeptide
Column(s):
Scherzo SW-C18 (250 x 3.0mm)
Scherzo SM-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

The Scherzo SM-C18 and SW-C18 columns can separate this glycopeptide with varying retention. The Scherzo SM-C18 has less retention while the Scherzo SW-C18 has more retention.

Application #:
TI0698
Type:
Application Note
Categories:
Biochemistry/Metabolism
Amino Acids and Peptides
Compounds:
L-glutamic acid
gamma-aminobutyric acid (GABA)
Column(s):
Scherzo SS-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)

The Scherzo SS-C18 column retains and separates glutamic acid and GABA better than a conventional C18 column

Application #:
TI0696
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
mandelic acid
hippuric acid
o-methylhippuric acid
m-methylhippuric acid
p-methylhippuric acid
Column(s):
Unison UK-C18 (150 x 3.0mm)
Unison UK-Phenyl (150 x 3.0mm)

Metabolites of toluene, xylene and stylene

Application #:
TI0695
Type:
Application Note
Categories:
Industrial Chemical
Compounds:
p-toluenesulfonyl semicarbazide (TSSC)
4,4'-oxybenzenesulfonyl hydrazide (OBSH)
Column(s):
Unison UK-C18 (150 x 3.0mm)

Blowing agents (OBSH, TSSC) for plastic materials

Application #:
TI0694
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
"L-glutamic acid
gammaaminobutyric acid (GABA)
3,4-dihydroxyL-phenylalanine (L-DOPA)
5-hydroxyindole- 3-acetic acid (5-HIAA)
L-tyrosine
L-noradrenaline (L-norepinephrine)
acetylcholine chloride
L-adrenaline (L-epinephrine)
5-hydroxyL-tryptophan
L-phenylalanine
dopamine
L-tryptophan
serotonin"
Column(s):
Scherzo SS-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Small, polar molecules like neurotransmitters are difficult to retain on a conventional C18 column like Unison UK-C18. Scherzo SS-C18 can retain these compounds much better than a standard Unison UK-C18 column, as well as resolve the peaks better. Conditions compatible with LC-MS

Application #:
TI0693
Type:
Application Note
Categories:
Food Chemistry
Compounds:
quinic acid
hydroxyhydroquinone
3,4-dihydroxyhydrocinnamic acid
caffeine
caffeic acid
p-coumaric acid
ferulic acid
isoferulic acid
Column(s):
Unison UK-C18 (250 x 4.6mm)

Unison UK-C18 column can separate out the small, polar molecule components of coffee bean extract due to the lower density of C18 ligands. The column can generate 219 peaks, which shows all of the components of the extract.

Application #:
TI0692
Type:
Application Note
Categories:
Food Chemistry
Compounds:
hydroxyhydroquinone
3,4-dihydroxyhydrocinnamic acid
caffeic acid
p-coumaric acid
caffeine
ferulic acid
isoferulic acid
Column(s):
Scherzo SW-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

Both Unison UK-C18 and Scherzo SW-C18 can separate out components of coffee extracts, but Scherzo SW-C18 can resolve the peaks of caffeine and ferulic acid better.

Application #:
TI0689
Type:
Application Note
Categories:
Botanicals
Pharmaceuticals and Cosmetics
Compounds:
trans-resveratrol
cis-resveratrol
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Cadenza CD-C18 (150 x 3.0mm)
Cadenza CW-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Presto FF-C18 (150 x 3.0mm)

All of the columns listed can recognize the structural difference between these two isomers, and resolve them into two separate peaks.

Application #:
TI0679
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
" acetaminophen
N-acetyl-4-benzoquinone imine"
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Acetaminophen and metabolite

Application #:
TI0678
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
" acetaminophen
N-acetyl-4-benzoquinone imine"
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Acetaminophen and metabolite

Application #:
TI0670
Type:
Application Note
Categories:
Biochemistry and Metabolism
Amino Acids and Peptides
Compounds:
creatine phosphate
betaine
L-carnitine
creatine
L-theanine
Column(s):
Scherzo SS-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Zwitterionic compounds

Application #:
TI0667
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
beta-endosulfan
alpha-endosulfan
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Cadenza CD-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Endosulfan isomers

Application #:
TI0662
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
penicillin G
methicillin
ampicillin
amoxicillin
carbenicillin
Column(s):
Scherzo SM-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)

Penicillin Antibiotics

Application #:
TI0659
Type:
Application Note
Categories:
Food Chemistry
Compounds:
(E)-beta-farnesene
Column(s):
Scherzo SM-C18 (250 x 4.6mm)
Cadenza CD-C18 (250 x 4.6mm)
Cadenza CL-C18 (250 x 4.6mm)
Unison UK-C18 (250 x 4.6mm)

Farnesene isomers

Application #:
TI0654
Type:
Application Note
Categories:
LC-MS
Industrial Chemical
Compounds:
ammonium acetate
acetonitrile
Column(s):
Unison UK-C18 (250 x 2.0mm)

LC/MS analysis of perfluorinated organic compounds (PFC's) in seawater

Application #:
TI0642
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
vanillylmandelic acid
mandelic acid
homovanillic acid
dopamine
Column(s):
Scherzo SM-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)

Scherzo is able to separate mandelic acid and dopamine, which coelute on a conventional C18 column (Unison UK-C18). This is possible because the ionic ligands recognize the small structural differences between the two compounds.

Application #:
TI0641
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
vanillylmandelic acid
mandelic acid
homovanillic acid
dopamine
Column(s):
Scherzo SM-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)

Catecholamine metabolites

Application #:
TI0640
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
dl-chlorpheniramine
dextromethorphan
propylparaben
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Cold medicine compounds

Application #:
TI0639
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
dl-chlorpheniramine
dextromethorphan
propylparaben
Column(s):
Cadenza CD-C18 (150 x 4.6mm)
Cadenza CW-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)
Unison UK-C8 (150 x 4.6mm)
Unison UK-Phenyl (150 x 4.6mm)

Cold medicine compounds

Application #:
TI0621
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
plerixafor
Column(s):
Unison UK-C18 (150 x 4.6mm)

Plerixafor (Chemokine receptor antagonist)

Application #:
TI0617
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
esculin
esculetin
7-hydroxycoumarin
coumarin
3,4-dihydrocoumarin
warfarin
Column(s):
Scherzo SM-C18 (150 x 4.6mm)
Cadenza CD-C18 (150 x 4.6mm)
Cadenza CW-C18 (150 x 4.6mm)
Cadenza CL-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)
Unison UK-C8 (150 x 4.6mm)
Unison UK-Phenyl (150 x 4.6mm)

Coumarins

Application #:
TI0599
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
NAD
NADP
NADH
NADPH
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Coenzymes (Nicotinamide adenine dinucleotides)

Application #:
TI0593
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
plerixafor
Column(s):
Unison UK-C18 (150 x 4.6mm)

Plerixafor (Chemokine receptor antagonist)

Application #:
TI0592
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
cetirizine
Column(s):
Scherzo SM-C18 (150 x 4.6mm)
Cadenza CD-C18 (150 x 4.6mm)
Cadenza CW-C18 (150 x 4.6mm)
Cadenza CL-C18 (150 x 4.6mm)
Cadenza HS-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)
Unison UK-C8 (150 x 4.6mm)
Unison UK-Phenyl (150 x 4.6mm)

Cetirizine (Antihistamine)

Application #:
TI0588
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
adenosine 5'- monophosphate disodium (AMP) guanosine 5'- monophosphate disodium (GMP)
adenosine 3'
5'-cyclic monophosphate sodium (cAMP)
guanosine 3'
5'-cyclic monophosphate sodium (cGMP)
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Cyclic mononucleotides (cAMP, cGMP)

Application #:
TI0581
Type:
Application Note
Categories:
Industrial Chemical
Environmental and Agricultural
Compounds:
Bisphenol A
Column(s):
Scherzo SM-C18 (75 x 4.6mm)
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CW-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Cadenza HS-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Bisphenol A

Application #:
TI0554
Type:
Application Note
Categories:
Vitamins
Compounds:
alpha-carotene and beta-carotene
Column(s):
Cadenza CD-C18 (150 x 4.6mm)
Cadenza CL-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)

Alpha-carotene and beta-carotene

Application #:
TI0552
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
sodium arsenite
dimethylarsinic acid (DMAA)
methylarsonic acid (MAA)
disodium hydrogenarsenate heptahydrate
Column(s):
Scherzo SM-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

Arsenic compounds

Application #:
TI0550
Type:
Application Note
Categories:
Food Chemistry
Compounds:
sucralose
Column(s):
Unison UK-C18 (250 x 4.6mm)

Sucralose by reversed-phase analysis

Application #:
TI0548
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
succinic acid
malic acid
fumaric acid
malonic acid
citric acid
tartaric acid
maleic acid
Column(s):
Scherzo SM-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

Organic acids (2)

Application #:
TI0546
Type:
Application Note
Categories:
Industrial Chemical
Compounds:
p-hydroxybenzoic acid
m-hydroxybenzoic acid
terephthalic acid
isophthalic acid
homophthalic acid
o-phthalic acid
hydroxybenzoic acid
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Aromatic carboxylic acids

Application #:
TI0544
Type:
Application Note
Categories:
Industrial Chemical
Pharmaceuticals & Cosmetics
Compounds:
Benzathonium chloride
Column(s):
Scherzo SM-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

Benzathonium chloride

Application #:
TI0543
Type:
Application Note
Categories:
Industrial Chemical
Pharmaceuticals & Cosmetics
Compounds:
benzalkonium chloride
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Benzalkonium chloride

Application #:
TI0539
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
adenine
guanine
hypoxanthine
xanthine
Column(s):
Scherzo SM-C18 (250 x 4.6mm)
Unison UK-C18 (250 x 4.6mm)

Purine bases

Application #:
TI0534
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
hydroxyzine
pamoic acid
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)

Hydroxyzine pamoate

Application #:
TI0533
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
fumaric acid
clemastine
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)

Clemastine fumarate

Application #:
TI0530
Type:
Application Note
Categories:
Biochemistry / Metabolism
Industrial Chemical
Compounds:
methyl lactate
lactic acid
levulinic acid
methyl levulinate
Column(s):
Scherzo SM-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)

Levulinic Acid, Lactic Acid and methyl Esters

Application #:
TI0529
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
ADP
AMP
ATP
Column(s):
Scherzo SM-C18 (30 x 3.0mm)
Unison UK-C18 (30 x 3.0mm)

Adenosine Phosphates

Application #:
TI0524
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
L-carnosine
L-anserine nitrate
Inosine 5' monophosphate dipotassium
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Anserine and Related Compounds

Application #:
TI0523
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
acetic acid
trifluoroacetic acid
trichloroacetic acid
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Acetic Acid and Trihaloacetic Acids

Application #:
TI0522
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
CMP
UMP
dCMP
dUMP
IMP
GMP
dTMP
AMP
dGMP
dAMP
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Mononucleotides

Application #:
TI0521
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
glutathione reduced (GSH)
glutathione oxidized (GSSG)
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)

Glutathiones

Application #:
TI0519
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
DL-mevalonolactone
DL-mevalonic acid
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Mevalonolactone and Mevalonic Acid

Application #:
TI0518
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
sodium gluconate
glyoxylic acid
lactic acid
malic acid
succinic acid
malonic acid
citric acid
fumaric acid
maleic acid
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Organic Acids

Application #:
TI0517
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
beta-estradiol 17-(beta-glucuronide)
17beta-estradiol
beta-estradiol 3
17 disulfate
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)

Estradiol and Metabolites

Application #:
TI0514
Type:
Application Note
Categories:
Botanicals
Compounds:
gibberellin A3
3-indoleacetic acid
abscisic acid
3-indolepropionic acid
jasmonic acid
3-indolebutyric acid
gibberellin A4
Column(s):
Cadenza CD-C18 (150 x 3.0mm)
Cadenza CW-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Cadenza HS-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Unison UK-C8 (150 x 3.0mm)
Unison UK-Phenyl (150 x 3.0mm)

Phytohormones

Application #:
TI0513
Type:
Application Note
Categories:
Botanicals
Compounds:
gibberellin A3
3-indoleacetic acid
abscisic acid
3-indolepropionic acid
jasmonic acid
3-indolebutyric acid
gibberellin A4
Column(s):
Cadenza CD-C18 (150 x 3.0mm)
Cadenza CW-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Cadenza HS-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Unison UK-C8 (150 x 3.0mm)
Unison UK-Phenyl (150 x 3.0mm)

Phytohormones

Application #:
TI0511
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
Zanamivir (Anti-flu medicine)
Column(s):
Unison UK-C18 (150 x 4.6mm)
Unison UK-Silica (150 x 4.6mm)
Unison UK-Amino (150 x 4.6mm)

Zanamivir (Anti-flu medicine)

Application #:
TI0510
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
Oseltamivir phosphate (Anti-flu medicine)
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Oseltamivir phosphate (Anti-flu medicine)

Application #:
TI0509
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
Paroxetine HCl (Antidepressant)
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Paroxetine HCl (Antidepressant)

Application #:
TI0508
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
Rilmazafone HCl (Benzodiazepine hypnotic)
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Rilmazafone HCl (Benzodiazepine hypnotic)

Application #:
TI0507
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
Zopiclone (Nonbenzodiazepine hypnotic)
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Zopiclone (Nonbenzodiazepine hypnotic)

Application #:
TI0506
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
Codeine phosphate (Narcotic antitussive)
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Codeine phosphate (Narcotic antitussive)

Application #:
TI0501
Type:
Application Note
Categories:
Column performance
Compounds:
acetaminophen
1-hydroxy-7-azabenzotriazole
prednisolone
methyl 3-amino-2-thiophenecarboxylate
6-alpha-methylprednisolone
corticosterone
4-aminobenzophenone
propylparaben
Column(s):
Scherzo SM-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)

Comparison of elution characteristics between Scherzo SM-C18 and Unison UK-C18

Application #:
TI0499
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
Pranoprofen (Nonsteroid anti-inflammatory drug:NSAID)
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Pranoprofen (Nonsteroid anti-inflammatory drug:NSAID)

Application #:
TI0498
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
Naftopidil (alpha1-receptor blocker)
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Naftopidil (alpha1-receptor blocker)

Application #:
TI0497
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
Furosemide (Diuretic)
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Furosemide (Diuretic)

Application #:
TI0496
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
Menatetrenone (Vitamin K)
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Menatetrenone (Vitamin K)

Application #:
TI0495
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
Mequitazine
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Mequitazine (Antihistamine)

Application #:
TI0494
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics / Steroids
Compounds:
Betamethasone
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Betamethasone (Antihistamine:Adrenal corticosteroid)

Application #:
TI0485
Type:
Application Note
Categories:
Botanicals
Compounds:
naringin
hesperidin
neohesperidin
neohesperidin dihydrochalcone
Column(s):
Cadenza CD-C18 (150 x 3.0mm)
Cadenza CW-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Unison UK-C8 (150 x 3.0mm)

Flavanone glycosides

Application #:
TI0483
Type:
Application Note
Categories:
Food Chemistry / Industrial Chemical
Compounds:
denatonium benzoate
Column(s):
Cadenza CD-C18 (50 x 3.0mm)
Cadenza CW-C18 (50 x 3.0mm)
Cadenza CL-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)

Denatonium benzoate

Application #:
TI0480
Type:
Application Note
Categories:
Botanicals
Compounds:
sulforaphane
allyl isothiocyanate
benzyl isothiocyanate
Column(s):
Cadenza CD-C18 (75 x 2.0mm)
Cadenza CW-C18 (75 x 2.0mm)
Cadenza CL-C18 (75 x 2.0mm)
Unison UK-C18 (75 x 2.0mm)
Unison UK-C8 (75 x 2.0mm)
Unison UK-Phenyl (75 x 2.0mm)

Isothiocyanates of Brassicaceae (Cruciferae)

Application #:
TI0479
Type:
Application Note
Categories:
Botanicals
Compounds:
sinigrin
sulforaphane
allyl isothiocyanate
benzyl isothiocyanate
Column(s):
Cadenza CW-C18 (75 x 2.0mm)
Cadenza CL-C18 (75 x 2.0mm)
Unison UK-C18 (75 x 2.0mm)
Unison UK-C8 (75 x 2.0mm)
Unison UK-Phenyl (75 x 2.0mm)

Isothiocyanates of Brassicaceae (Cruciferae)

Application #:
TI0465
Type:
Application Note
Categories:
Natural Compounds
Compounds:
Lycopene
Column(s):
Cadenza CD-C18 (150 x 4.6mm)
Cadenza CW-C18 (150 x 4.6mm)
Cadenza CL-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)

Lycopene

Application #:
TI0458
Type:
Application Note
Categories:
Industrial Chemicals
Pharmaceuticals & Cosmetics
Compounds:
ethylenediamine
diethylenetriamine
triethylenetetramine
tetraethylenepentamine
Column(s):
Unison UK-C18 (75 x 3.0mm)

Aliphatic Amines

Application #:
TI0457
Type:
Application Note
Categories:
Industrial Chemicals
Food Chemistry
Environmental and Agricultural
Compounds:
sudan I
sudan II
sudan III
sudan IV
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CW-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Sudan Dyes

Application #:
TI0456
Type:
Application Note
Categories:
Industrial Chemicals
Food Chemistry
Environmental and Agricultural
Compounds:
leucomalachite green
malachite green
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CW-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)
Unison UK-C8 (75 x 3.0mm)
Unison UK-Phenyl (75 x 3.0mm)

Malachite Green and Metabolite

Application #:
TI0453
Type:
Application Note
Categories:
Industrial Chemicals
Compounds:
methacrylamide
acrylonitrile
acrylamide
acrolein
Column(s):
Cadenza CL-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)
Unison UK-Phenyl (250 x 3.0mm)

Acrylic Monomers

Application #:
TI0436
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
vancomycin
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CW-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)

Antibiotic (Vancomycin)

Application #:
TI0435
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
tylosin
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CW-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)

Antibiotic (Tylosin)

Application #:
TI0434
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
rifampicin
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CW-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)

Antibiotic (Rifampicin)

Application #:
TI0426
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
tobramycin sulfate
streptomycin sulfate
kanamycin sulfate
gentamicin sulfate
amikacin disulfate
Column(s):
Cadenza CD-C18 (250 x 3.0mm)
Cadenza CW-C18 (250 x 3.0mm)
Cadenza CL-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

Aminoglycoside Antibiotics

Application #:
TI0419
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
microcystin YR
microcystin RR
microcystin LR
Column(s):
Cadenza CD-C18 (150 x 3.0mm)
Cadenza CW-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Unison UK-C8 (150 x 3.0mm)
Unison UK-Phenyl (150 x 3.0mm)

Microcystins

Application #:
TI0412
Type:
Application Note
Categories:
Environmental and Agricultural
Industrial Chemicals
Compounds:
perfluorooctanoic acid
perfluorooctanesulfonic acid
perfluorobutanesulfonic acid
Column(s):
Cadenza CD-C18 (75 x 2.0mm)
Cadenza CW-C18 (75 x 2.0mm)
Cadenza CL-C18 (75 x 2.0mm)
Unison UK-C18 (75 x 2.0mm)
Unison UK-C8 (75 x 2.0mm)
Unison UK-Phenyl (75 x 2.0mm)

PFAAs

Application #:
TI0396
Type:
Application Note
Categories:
LC-MS
Environmental and Agricultural
Compounds:
methamidophos
dichlorvos
Column(s):
Unison UK-C18 (50 x 2.0mm)

LC-MS/MS Application - Organophosphorous Pesticides

Application #:
TI0388
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
calcitonin acetate
salmon (MW 3492)
Column(s):
Cadenza CD-C18 (100 x 3.0mm)
Cadenza CW-C18 (100 x 3.0mm)
Cadenza CL-C18 (100 x 3.0mm)
Unison UK-C18 (100 x 3.0mm)
Unison UK-Amino (100 x 3.0mm)

Calcitonin, salmon

Application #:
TI0378
Type:
Application Note
Categories:
Food Chemistry
Compounds:
sodium sulfamate (aminosulfonic acid sodium salt)
cyclamic acid (N-cyclohexylsulfamic acid)
? cyclamic acid (N-cyclohexylsulfamic acid)
Column(s):
Unison UK-C18 (50 x 3.0mm)
Unison UK-Amino (50 x 3.0mm)

Sulfamic acid and cyclamic acid can be separated by either reversed phase or normal phase chromatography. Reversed phase gives better peak shape while normal phase gives better run time.

Application #:
TI0375
Type:
Application Note
Categories:
Steroids
Biochemistry / Metabolism
Compounds:
beta-Estradiol 3,17-disulfate
beta-Estradiol 17-(beta-D-glucuronide)
17-beta-estradiol
Column(s):
Cadenza CD-C18 (30 x 2.0mm)
Cadenza CW-C18 (30 x 2.0mm)
Cadenza CL-C18 (30 x 2.0mm)
Unison UK-C18 (30 x 2.0mm)
Unison UK-C8 (30 x 2.0mm)
Unison UK-Phenyl (30 x 2.0mm)

Many Cadenza and Unison columns achieve excellent resolution with beta-Estradiol 3,17-disulfate and 17beta-estradiol despite their similar structures.

Application #:
TI0374
Type:
Application Note
Categories:
Amino Acids and Peptides
Compounds:
angiotension IV
angiotension III
angiotension II
angiotension I (human)
angiotension I (bovine)
Column(s):
Unison UK-C18 (150 x 3.0mm)
Unison UK-Amino (150 x 3.0mm)

Unison UK-Amino separates Angiotensin III and Angiotensisn II better than a standard reverse phased column.

Application #:
TI0371
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
propyl-L-arginine (N-PLA)
monomethyl-L-arginine (L-NMMA)
dimetyl-L-arginine (SDMA)
dimetyl-L-arginine (ADMA)
Column(s):
Unison UK-C18 (150 x 4.6mm)

Unison UK-C18 successfully separates methylated arginines of similar structure. Compounds are pre-column derivatized to enable fluroescence detection.

Application #:
TI0370
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
6-nitronorepine
6-nitroepinephrine
6-nitrodopamine
Column(s):
Unison UK-C18 (250 x 4.6mm)

Unison UK-C18 successfully separates nitroNE, nitroE, and nitroDA. Detection is via post-column derivatization.

Application #:
TI0348
Type:
Application Note
Categories:
Food Chemistry
Compounds:
tartaric acid
succinic acid
propionic acid
malonic acid
lactic acid
fumaric acid
formic acid
citric acid
acetic acid
Column(s):
Cadenza CL-C18 (250 x 4.6mm)
Unison UK-C18 (250 x 4.6mm)

Organic acids

Application #:
TI0347
Type:
Application Note
Categories:
Oligosaccharides
Compounds:
maltooligosaccharide
Column(s):
Unison UK-C18 (250 x 3.0mm)
Unison UK-Amino (250 x 3.0mm)

Maltooligosaccharides

Application #:
TI0346
Type:
Application Note
Categories:
Oligosaccharides
Compounds:
D-glucosamine
chitosan trimer
chitosan tetramer
chitosan pentamer
chitosan hexamer
chitosan dimer
Column(s):
Unison UK-C18 (150 x 3.0mm)
Unison UK-Amino (250 x 3.0mm)

Chitosanoligosaccharides

Application #:
TI0340
Type:
Application Note
Categories:
Botanicals
Compounds:
wogonin
sutellarein
epigallocatechin gallate
epigallocatechin
epicatechin gallate
epicatechin
catechin
baicalin
baicalein
Column(s):
Unison UK-C18 (250 x 4.6mm)

Catechins and flavonoids

Application #:
TI0323
Type:
Application Note
Categories:
Column Performance
Steroids
Compounds:
progesterone
deoxycorticosterone acetate
estrone
estradiol
corticosterone
ethinylestradiol
cortisone
prednisone
6 alpha-methylprednisolone
hydrocortisone
prednisolone
estriol
Column(s):
Cadenza CD-C18 (250 x 4.6mm)
Cadenza CL-C18 (250 x 4.6mm)
Unison UK-C18 (250 x 4.6mm)
Unison UK-C8 (250 x 4.6mm)
Unison UK-Phenyl (250 x 4.6mm)

Steroid Hormones

Application #:
TI0319
Type:
Application Note
Categories:
Column Performance
Steroids
Compounds:
progesterone
deoxycorticosterone acetate
estrone
estradiol
corticosterone
ethinylestradiol
cortisone
prednisone
6 alpha-methylprednisolone
hydrocortisone
prednisolone
estriol
Column(s):
Unison UK-C18 (250 x 4.6mm)
Unison UK-Amino (250 x 4.6mm)

Steroids

Application #:
TI0312
Type:
Application Note
Categories:
Vitamins
LC-MS
Compounds:
thiamine
riboflavin
pyridoxine
pantothenic acid
nicotinamide
Folic acid
biotin
ascorbic acid
Column(s):
Unison UK-C18 (250 x 2.0mm)

LC-MS/MS Water Soluble Vitamins

Application #:
TI0303
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
minoxidil sulfate
minoxidil
Column(s):
Cadenza CD-C18 (150 x 4.6mm)
Cadenza CW-C18 (150 x 4.6mm)
Cadenza CL-C18 (150 x 4.6mm)
Cadenza HS-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)
Unison UK-C8 (150 x 4.6mm)
Unison UK-Phenyl (150 x 4.6mm)

Minoxidil and metabolite

Application #:
TI0299
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
Anions
Column(s):
Cadenza CW-C18 (150 x 4.6mm)
Cadenza CL-C18 (150 x 4.6mm)
Cadenza HS-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)
Unison UK-C8 (150 x 4.6mm)
Unison UK-Phenyl (150 x 4.6mm)

Anions

Application #:
TI0298
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
Anions
Column(s):
Unison UK-C18 (150 x 4.6mm)

Anions

Application #:
TI0294
Type:
Application Note
Categories:
Botanicals
Compounds:
quercitrin
quercetin
isoquercitrin
ellagic acid
chlorogenic acid
caffeic acid
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Cadenza HS-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)
Unison UK-C8 (75 x 3.0mm)
Unison UK-Phenyl (75 x 3.0mm)

Polyphenol, berry

Application #:
TI0288
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
verapamil
progesterone
Column(s):
Cadenza CD-C18 (150 x 4.6mm)
Cadenza CL-C18 (150 x 4.6mm)
Cadenza HS-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)

Verapamil

Application #:
TI0277
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
Morantel Citrate
Column(s):
Cadenza CD-C18 (150 x 4.6mm)
Cadenza HS-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)

Morantel Citrate

Application #:
TI0269
Type:
Application Note
Categories:
Vitamins
Compounds:
thiamine
riboflavin
pyridoxine
pyridoxal
nicotinic acid
L-ascorbic acid
folic acid
caffeine
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)

Waters soluble vitamins

Application #:
TI0268
Type:
Application Note
Categories:
Vitamins
Compounds:
thiamine
pyridoxine
pyridoxamine
pyridoxal
p-aminobenzoic acid
orotic acid
nicotinic acid
nicotinamide
L-ascorbic acid
Column(s):
Unison UK-C18 (75 x 4.6mm)

Water soluble vitamins

Application #:
TI0267
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
ddl (2'3'-dideoxyinosine)
d4T (2'3'-didehydro-3'-deoxythymidine)
AZT (azidothymidine)
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)

Anti-HIV nucleosides

Application #:
TI0264
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
scoporamine hydrobromide
butylscopalamine bromide
atropine sulfate
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)

Parasympatholytics

Application #:
TI0260
Type:
Application Note
Categories:
Column Performance
Compounds:
benzylalcohol
bromovalerylurea
o-ethoxybenzamide (ethenzamide)
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)

Pi-dipole interaction on CL-C18

Application #:
TI0259
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
sulfanilamide
sulfacetamide
sulfadiazine
sulfathiazole
sulfapyridine
sulfamerazine
sulfamethazine (sulfadimidin)
sulfamethoxypyridazine
sulfamethoxazole
sulfamonomethoxine
sulfisoxazole
sulfabenzamide
sulfadimethoxine
sulfaquinoxaline
sulfanitran
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)

Sulfonamides

Application #:
TI0258
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
sulfisoxazole
sulfathiazole
sulfaquinoxaline
sulfamonomethoxine
sulfamethoxazole
sulfamethazine (sulfadimidin)
sulfamerazine
sulfadiazine
Column(s):
Cadenza CD-C18 (30 x 2.0mm)
Cadenza CL-C18 (30 x 2.0mm)
Unison UK-C18 (30 x 2.0mm)

Sulfonamides

Application #:
TI0257
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
uric acid
oxalic acid
L-ascorbic acid
Column(s):
Unison UK-C18 (250 x 4.6mm)

Causative Substances of Urolithiasis

Application #:
TI0256
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
phenylbutazone
oxyphenbutazone
naproxen
meclofenamic acid sodium salt
ketoprofen
flunixin
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)

NSAIDs

Application #:
TI0252
Type:
Application Note
Categories:
Column Performance
Compounds:
Triphenylene
Phenol
o-Terphenyl
Caffeine
Butylbenzene
Amylbenzene
Column(s):
Cadenza CD-C18 (0 x 0mm)
Cadenza CL-C18 (0 x 0mm)
Unison UK-C18 (0 x 0mm)

Basic interaction of CL-C18, CD-C18, and UK-C18

Application #:
TI0248
Type:
Application Note
Categories:
LC-MS
Environmental and Agricultural
Compounds:
trichloroacetic acid (TCAA)
monochloroacetic acid (MCAA)
dichloroacetic acid (DCAA)
Column(s):
Unison UK-C18 (75 x 3.0mm)

LC-MS halo acetic acids

Application #:
TI0245
Type:
Application Note
Categories:
Column Performance
Biochemistry / Metabolism
Compounds:
theophylline
phenol
caffeine
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)

Retention behavior of polar compounds

Application #:
TI0243
Type:
Application Note
Categories:
Vanillin and Guaiacol Derivatives
Compounds:
vanillin
guaiacol
ethylvanillin
4-methylguaiacol
4-ethylguaiacol
Column(s):
Cadenza CD-C18 (100 x 4.6mm)
Cadenza CL-C18 (100 x 4.6mm)
Unison UK-C18 (100 x 4.6mm)
Unison UK-C8 (100 x 4.6mm)
Unison UK-Phenyl (100 x 4.6mm)

Application #:
TI0241
Type:
Application Note
Categories:
Dihydrouracil
Compounds:
‚„ihydrouracil
uracil
Column(s):
Cadenza CD-C18 (250 x 4.6mm)
Unison UK-C18 (250 x 4.6mm)

Application #:
TI0239
Type:
Application Note
Categories:
Halo Acetic Acids
Compounds:
monochloroacetic acid (MCAA)
dichloroacetic acid (DCAA)
trichloroacetic acid (TCAA)
bromochloroacetic acid (BCAA)
monobromoacetic acid (MBAA)
dibromoacetic acid (DBAA)
tribromoacetic acid (TBAA)
Column(s):
Cadenza CL-C18 (250 x 4.6mm)
Unison UK-C18 (250 x 4.6mm)

Halo acetic acids

Application #:
TI0238
Type:
Application Note
Categories:
Stevia Sweeteners
Compounds:
rebaudioside A
stevioside
Column(s):
Cadenza CD-C18 (250 x 4.6mm)
Cadenza CL-C18 (250 x 4.6mm)
Unison UK-C18 (250 x 4.6mm)

Stevia sweeteners

Application #:
TI0235
Type:
Application Note
Categories:
Agricultural Chemicals (10)
Compounds:
iminoctadine (guazatine)
Column(s):
Unison UK-C18 (100 x 4.6mm)

Agricultural chemicals

Application #:
TI0229
Type:
Application Note
Categories:
Synthetic Antimicrobial (Enrofloxacin)
Compounds:
enrofloxacin
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)

Enrofloxacin

Application #:
TI0228
Type:
Application Note
Categories:
Chlorophyll and carotenoid
Compounds:
lutein (xanthophyll)
chlorophyll b
chlorophyll a
beta-carotene
Column(s):
Unison UK-C18 (100 x 4.6mm)

Chlorophyll and carotenoid

Application #:
TI0227
Type:
Application Note
Categories:
ELSD
Compounds:
taurine
thiamine (B1)
pyridoxine (B6)
nicotinamide (B3),
Column(s):
Unison UK-C18 (75 x 4.6mm)

LC-ELSD of taurine and water soluble vitamins

Application #:
TI0226
Type:
Application Note
Categories:
Creatine Metabolites
Compounds:
creatine
creatine phosphate
creatinine
Column(s):
Unison UK-C18 (250 x 4.6mm)

Separation of creatine and related polar metabolites with 100% aqueous mobile phase, using the UK-C18, which excels in the separation of highly polar compounds.

Application #:
TI0225
Type:
Application Note
Categories:
Fat-Soluble Vitamins
Compounds:
alpha-tocopherol
beta-carotene
coenzyme Q10
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Comparison of several reverse phase columns in the high-speed separation of fat-soluble vitamins.

Application #:
TI0222
Type:
Application Note
Categories:
Antibiotic
Compounds:
bacitracin
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)
Unison UK-C8 (75 x 3.0mm)
Unison UK-Phenyl (75 x 3.0mm)

Analysis of the annular peptide antibiotic bacitracin using various reverse phase columns. Each column produces excellent peaks using gradient elution and TFA modifier.

Application #:
TI0221
Type:
Application Note
Categories:
Antibiotic
Compounds:
colistin
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)
Unison UK-C8 (75 x 3.0mm)
Unison UK-Phenyl (75 x 3.0mm)

Analysis of the annular peptide antibiotic colistin, which targets the plasma membrane of gram negative bacteria, using various reverse phase columns. All columns achieve excellent separation of colistin isotomers using gradient elution and TFA modifier.

Application #:
TI0220
Type:
Application Note
Categories:
Antibiotic
Compounds:
spiramycin
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)
Unison UK-C8 (75 x 3.0mm)
Unison UK-Phenyl (75 x 3.0mm)

Analysis of the macrolide antibiotic spiramycin using various reverse phase columns. Each column produces a sharp peak with TFA mobile phase.

Application #:
TI0218
Type:
Application Note
Categories:
Veterinary Medicine (Synthetic Antimicrobial)
Compounds:
salinomycin
Column(s):
Unison UK-C18 (75 x 3.0mm)
Unison UK-Phenyl (75 x 3.0mm)

Analysis of salinomycin, a common antibiotic additive to animal feed. Note the incredible peak produced by the UK Phenyl column.

Application #:
TI0217
Type:
Application Note
Categories:
Veterinary Medicine (Synthetic Antimicrobial)
Compounds:
lasalocid
Column(s):
Unison UK-C18 (75 x 3.0mm)
Unison UK-C8 (75 x 3.0mm)
Unison UK-Phenyl (75 x 3.0mm)

Analysis of lasalocid, a common antibiotic additive to animal feed, in acid. Each column produces an excellent peak.

Application #:
TI0216
Type:
Application Note
Categories:
Antibiotic
Compounds:
oxytetracycline
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)
Unison UK-C8 (75 x 3.0mm)
Unison UK-Phenyl (75 x 3.0mm)

Analysis of the antibiotic oxytetracycline, which impedes protein synthesis, using various reverse phase columns. Excellent peaks are produced by all columns in acidic conditions.

Application #:
TI0215
Type:
Application Note
Categories:
Antibiotic
Compounds:
ampicillin
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)
Unison UK-C8 (75 x 3.0mm)
Unison UK-Phenyl (75 x 3.0mm)

Analysis of penicillin, which impedes synthesis of the bacterial cell wall, using various reverse phase columns. Under acidic conditions all columns produce excellent peaks.

Application #:
TI0213
Type:
Application Note
Categories:
Synthetic Antimicrobial
Compounds:
thiamphenicol
Column(s):
Unison UK-C18 (75 x 3.0mm)
Unison UK-C8 (75 x 3.0mm)
Unison UK-Phenyl (75 x 3.0mm)

Analysis of the synthetic veterinary antibiotic thiamphenicol, which impedes protein synthesis, under neutral pH. The C18, C8 and Phenyl columns all produce excellent peaks.

Application #:
TI0212
Type:
Application Note
Categories:
Veterinary Medicine (Synthetic Antimicrobial)
Compounds:
levamisol
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)
Unison UK-C8 (75 x 3.0mm)
Unison UK-Phenyl (75 x 3.0mm)

Analysis of the anthelminthic veterinary drug levamisol. Our reverse phase column with superior end-capping produces excellent peaks under neutral conditions.

Application #:
TI0211
Type:
Application Note
Categories:
Veterinary Medicine (Synthetic Antimicrobial)
Compounds:
oxolinic acid
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)
Unison UK-C8 (75 x 3.0mm)
Unison UK-Phenyl (75 x 3.0mm)

Analysis of the veterinary antimicrobrial oxolinic acid produces excellent peaks with various reverse phase columns.

Application #:
TI0210
Type:
Application Note
Categories:
Veterinary Medicine (Synthetic Antimicrobial)
Compounds:
nifurstyreneate monosodium salt (NFS)
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)
Unison UK-C8 (75 x 3.0mm)
Unison UK-Phenyl (75 x 3.0mm)

Analysis of nifurstyreneate monosodium salt, a veterinary antimicrobial nitrofuran used on fish, using various reverse phase columns.

Application #:
TI0208
Type:
Application Note
Categories:
Anilines
Compounds:
aniline
N-methylaniline
N,N-dimethylaniline
Column(s):
Unison UK-C18 (75 x 4.6mm)

Aniline, methylaniline and dimethylaniline separation with UK-C18.

Application #:
TI0203
Type:
Application Note
Categories:
Utilizing a high-throughput column for enzymatic reaction analysis
Compounds:
p-nitorophenyl-beta-glucoside
p-nitrophenol
Column(s):
Unison UK-C18 (10 x 2.0mm)

Analysis of enzymatic reaction using a high throughput 10 mm column.

Application #:
TI0202
Type:
Application Note
Categories:
Compounds:
alkyl parabens
Column(s):
Unison UK-C18 (10 x 2.0mm)

Our 10 mm long column can be used instead of a conventional 20-35mm column, performing high-speed separation in approximately 20 seconds while reducing column length. Furthermore our 10mm column has an impressive lifetime of over 2000 injections.

Application #:
TI0200
Type:
Application Note
Categories:
Out of elution order by electrostatic interaction
Compounds:
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

The effect of electrostatic interaction on retention. Hydrophobic interaction, which depends on hydrogen bonding capacity and dipole-dipole interaction, affects the retention time of analysis on different columns.

Application #:
TI0199
Type:
Application Note
Categories:
Adrenergic Amines
Compounds:
octopamine
synephrine
Column(s):
Unison UK-C18 (75 x 2.0mm)

Separation of synephrine, found in the fruit of the Sour Orange Tree, and and octopamine, which operates on the sympathetic nervous system.

Application #:
TI0198
Type:
Application Note
Categories:
Antioxidants
Compounds:
Irganox 1010
Irgafos 168
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-Silica (250 x 4.6mm)

Analysis for antioxidants of plastics in food.

Application #:
TI0196
Type:
Application Note
Categories:
Digitalis Glycosides
Compounds:
digoxigenin
digoxin
digitoxigenin
digitoxin
Column(s):
Unison UK-C18 (75 x 4.6mm)

Separation of the cardiac agent digitalis glycoside and its aglycon.

Application #:
TI0195
Type:
Application Note
Categories:
Coenzyme Q10
Compounds:
coenzymeQ10 (ubiquinone-10)
Column(s):
Cadenza CD-C18 (75 x 3.0mm)
Cadenza CL-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)
Unison UK-C8 (75 x 3.0mm)
Unison UK-Silica (150 x 3.0mm)

Analysis of coenzyme Q10, a dietary supplement used for its antioxidant action, with various columns.

Application #:
TI0193
Type:
Application Note
Categories:
GDP-Sugars (Sugar-nucleotides)
Compounds:
GDP-mannose
GDP-galactose
Column(s):
Unison UK-C18 (250 x 4.6mm)

Application #:
TI0192
Type:
Application Note
Categories:
UDP-Sugars (Sugar-nucleotides)
Compounds:
UDP-arabinose
UDP-glucose
UDP-xylose
Column(s):
Unison UK-C18 (250 x 4.6mm)

Separation of UDP-sugars, intermediates in sugar chain synthesis, the molecular structure of which differs only in the sugar group.

Application #:
TI0190
Type:
Application Note
Categories:
Short-Chain Fatty Acids
Compounds:
n-propionic acid
n-butyric acid
n-valeric acid
n-caproic acid
Column(s):
Unison UK-C18 (50 x 4.6mm)
Unison UK-C8 (50 x 4.6mm)
Unison UK-Phenyl (50 x 4.6mm)

Separation of short chain cable fatty acids without modifying the functional group.

Application #:
TI0184
Type:
Application Note
Categories:
Gamma-Aminobutyric Acid
Compounds:
gamma-aminobutyric acid
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-Silica (250 x 2.0mm)

Normal phase separation of the neurotransmitter GABA.

Application #:
TI0183
Type:
Application Note
Categories:
Adreno-corticosteroids
Compounds:
aldosterone,
Column(s):
Cadenza CD-C18 (250 x 4.6mm)
Cadenza CL-C18 (250 x 4.6mm)
Unison UK-C18 (250 x 4.6mm)

Simultaneous analysis of compounds involved in the synthesis of andrenal corticosteroids.

Application #:
TI0182
Type:
Application Note
Categories:
Antifungal Drugs
Compounds:
econazole nitrate
miconazole nitrate
Column(s):
Unison UK-C18 (150 x 4.6mm)

Separation of the structurally similar antifungal drugs econazole and miconazole.

Application #:
TI0181
Type:
Application Note
Categories:
Xanthine Oxidase Related Compounds
Compounds:
uric acid
hypoxanthine
xanthine
allopurinol
Column(s):
Unison UK-C18 (75 x 4.6mm)

This analysis of xanthine oxydase related compounds includes separation of its substrate, product and inhibitor.

Application #:
TI0179
Type:
Application Note
Categories:
Purine Nucleotide Metabolites (Reversed-Phase)
Compounds:
inosine
hypoxanthine
guanine
xanthine
uric acid
allantoin
allantoic acid
glyoxylic acid
urea
Column(s):
Unison UK-C18 (250 x 3.0mm)

Reverse phase analysis of purine nucleotide metabolites, including uric acid and allantoin.

Application #:
TI0176
Type:
Application Note
Categories:
5-Fluorouracil (5-FU)
Uracil
Compounds:
uracil
5-fluorouracil
Column(s):
Cadenza CL-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Reverse phase separation of the highly polar compounds uracil and fluorouracil, which is an anti-cancer drug.

Application #:
TI0175
Type:
Application Note
Categories:
Vitamin
Compounds:
cyanocobalamin
hydroxocobalamin
Column(s):
Unison UK-C18 (150 x 4.6mm)

Gradient elution of cobalamin.

Application #:
TI0174
Type:
Application Note
Categories:
Catecholamines
Compounds:
L-norepinephrine
octopamine
L-epinephrine
dopamine
serotonin
Column(s):
Unison UK-C18 (75 x 4.6mm)

Analysis of the highly polar catecholamines. The ion pair reagent, not included, is separated by the mobile phase.

Application #:
TI0170
Type:
Application Note
Categories:
L-Carnitine
Compounds:
L-carnitine
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-Silica (150 x 3.0mm)

The polar compound L-Carnitine, analyzed in both normal and reverse phase modes.

Application #:
TI0165
Type:
Application Note
Categories:
Antipyretic Analgesics
Compounds:
acetaminophen
caffeine
salicylamide
promethazine methylenedisalicylate
Column(s):
Unison UK-C18 (75 x 3.0mm)

Analysis of antipyretic analgesics.

Application #:
TI0164
Type:
Application Note
Categories:
Calcium Pantothenate and Ascorbic Acid
Compounds:
calcium pantothenate
ascorbic acid
Column(s):
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)
Unison UK-Silica (150 x 4.6mm)

Analysis of highly polar vitamins under normal and reverse phase modes.

Application #:
TI0163
Type:
Application Note
Categories:
Simultaneous Analysis Of Water-soluble And Fat-soluble Vitamins
Compounds:
nicotinamide
pyridoxine
riboflavin
thiamine
retinol
ergocalciferol
Column(s):
Unison UK-C18 (75 x 3.0mm)

Application #:
TI0161
Type:
Application Note
Categories:
Antioxidants
Compounds:
butylhydroquinone (TBHQ),
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Analysis of an antioxidant food additives.

Application #:
TI0160
Type:
Application Note
Categories:
Riboflavin Tetrabutyrate Tablet
Compounds:
riboflavin tetrabutyrate
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Analysis of vitamin in tablet form.

Application #:
TI0157
Type:
Application Note
Categories:
Pyridoxine HCl (Vitamin B6) Injection Solution
Compounds:
pyridoxine HCl
Column(s):
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Analysis of vitamin B6 with neutral mobile phase in reverse phase mode.

Application #:
TI0156
Type:
Application Note
Categories:
Thiamine HCl (Vitamin B1) Injection Solution
Compounds:
thiamine HCl
Column(s):
Cadenza CL-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Analysis of vitamin B1 with neutral mobile phase in reverse phase mode.

Application #:
TI0155
Type:
Application Note
Categories:
Ascorbic Acid and Related Compounds
Compounds:
L-ascorbic acid
isoascorbic acid (erysorbic acid)
L-ascorbic acid 2-glucoside
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)

For analysis of ascorbic acid and related compounds, our 3um UK-C18 and 5um US-C18 can perform equivalent separations at high speed.

Application #:
TI0152
Type:
Application Note
Categories:
Nucleoside and Bases
Compounds:
cytosine
uracil
cytidine
guanine
uridine
thymine
adenine
guanosine
thymidine
Column(s):
Unison UK-C18 (250 x 4.6mm)
Unison UK-C18 (500 x 4.6mm)

In comparison with the 500mm column, our 3um 250mm separates with high efficiency.

Application #:
TI0151
Type:
Application Note
Categories:
Caproic Acid and Isomers
Compounds:
3-methylvaleric acid
2-methylvaleric acid
4-methylvaleric acid
n-caproic acid
Column(s):
Unison UK-C18 (250 x 4.6mm)
Unison UK-C18 (500 x 4.6mm)

Caproic acid and its methylvaleric acid isomers are separated with high resolution using our 500mm long column.

Application #:
TI0145
Type:
Application Note
Categories:
Catechins in Green Tea
Compounds:
epigallocatechin
catechin
caffeine
epigallocatechin gallate
epicatechin
epicatechin gallate
Column(s):
Unison UK-C18 (75 x 4.6mm)

Analysis of catechin additives to green tea with Unison UK-C18.

Application #:
TI0143
Type:
Application Note
Categories:
Methoxyphenol Isomers
Compounds:
o-methoxyphenol
p-methoxyphenol,
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Separation of isomers of the polymerization inhibitor methoxyphenol.

Application #:
TI0142
Type:
Application Note
Categories:
Hydroquinone Isomers (Dihydroxybenzene)
Compounds:
hydroquinone
resorcinol
catechol
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Separation of isomers of the polymerization inhibitor hydroquinine.

Application #:
TI0141
Type:
Application Note
Categories:
Ascorbic Acid Derivative
Compounds:
L-ascorbic acid
L-ascorbic acid 2-glucoside
nicotinamide
Column(s):
Unison UK-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 4.6mm)
Unison US-C18 (150 x 4.6mm)

Rapid analysis of ascorbic acid derivatives, including nicotinamide, under basic conditions.

Application #:
TI0140
Type:
Application Note
Categories:
Isoflavones 4
Compounds:
wighteone
7-O-methyl-lutenone
7,2'-di-O-methyl-lutenone
lupalbigenin
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Analysis of Isoflavones 4 in ammonium acetate.

Application #:
TI0139
Type:
Application Note
Categories:
Isoflavones 3
Compounds:
5-O-methylgenistein
genistein
prunetin
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Analysis of isoflavones 3 in ammonium acetate.

Application #:
TI0138
Type:
Application Note
Categories:
Isoflavones 2
Compounds:
2,3-dehydrokievitone
lutenone,
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Analysis of isoflavones 4 in ammonium acetate. (Should be 2 according to TI)

Application #:
TI0137
Type:
Application Note
Categories:
Isoflavones 1
Compounds:
5-O-methylgenistein
2'-hydroxygenistein
genistein
piscidone
2,3-dehydrokievitone
lutenone
prunetin
licoisoflavone A
lupiwighteone
wighteone
7-O-methyl-lutenone
derrone
alpinumisoflavone
7,2'-di-O-methyl-lutenone
lupalbigenin
Column(s):
Unison UK-C18 (250 x 4.6mm)

Simultaneous analysis of 15 types of isoflavones with gradient elution.

Application #:
TI0136
Type:
Application Note
Categories:
Caproic Acid Isomers
Compounds:
3-methylvaleric acid
2-methylvaleric acid
4-methylvaleric acid
n-caproic acid
Column(s):
Unison UK-C18 (250 x 4.6mm)
Unison UK-C8 (250 x 4.6mm)
Unison UK-Phenyl (250 x 4.6mm)

Analysis of methyl valeric acid and other caproic acid isomers, comparing separation by column.

Application #:
TI0134
Type:
Application Note
Categories:
Pyrethrins
Compounds:
Pyrethrin I
Pyrethrin II
Cinerin I
Cinerin II
Jasmolin I
Jasmolin II
allethrin
Column(s):
Unison UK-C18 (100 x 4.6mm)

Analysis of pyrethrin, an active ingredient in painted daisies.

Application #:
TI0133
Type:
Application Note
Categories:
Purine Nucleotides
Compounds:
hypoxanthine
inosine
inosine 5'-monophosphate (IMP)
adenosine 5'-monophosphate (AMP)
adenosine 5'-diphosphate (ADP)
adenosine 5'-triphosphate (ATP)
Column(s):
Unison UK-C18 (75 x 4.6mm)

Analysis of purine nucleotides under LC-MS conditions.

Application #:
TI0132
Type:
Application Note
Categories:
Urea
Compounds:
urea
Column(s):
Unison UK-C18 (250 x 4.6mm)

Reverse phase analysis of dye-labeled urea, a highly polar compound.

Application #:
TI0130
Type:
Application Note
Categories:
TCA cycle
Compounds:
oxalacetic acid
malic acid
alpha-ketoglutaric acid
succinic acid,
Column(s):
Unison UK-C18 (250 x 4.6mm)

Simultaneous analysis of Citric Acid Cycle compounds using our UK-C18 column.

Application #:
TI0129
Type:
Application Note
Categories:
Ornithine Cycle
Compounds:
urea
fumaric acid
citrulline
ornithine
argininosuccinic acid
arginine
Column(s):
Unison UK-C18 (250 x 4.6mm)

Simultaneous analysis of Ornithine Cycle comounds using our UK-C18, which has affinity for highly polar compounds.

Application #:
TI0128
Type:
Application Note
Categories:
PQQ (pyrroloquinoline quinone)
Compounds:
PQQ (pyrroloquinoline quinone)
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Analysis of PQQ, which has recently been identified as a possible vitamin in mammals.

Application #:
TI0124
Type:
Application Note
Categories:
Column Performance
Compounds:
Propylparaben
Prednisolone
methyl 3-amino-2-thiophenecarboxylate
Corticosterone
Acetaminophen
6-alpha-methylprednisolone
4-aminobenzophenone
1hydroxy-7-azabenzotriazole
Column(s):
Unison UK-C18 (75 x 4.6mm)

Unison UK-C18 batch to batch reproducibility

Application #:
TI0120
Type:
Application Note
Categories:
Copper Chlorophylline
Compounds:
chlorophylline
Column(s):
Unison UK-C18 (75 x 4.6mm)

Analysis of copper chlorophylline, a chlorophyll derived food additive.

Application #:
TI0118
Type:
Application Note
Categories:
pH Stability of Unison Series
Compounds:
propylbenzoate
Column(s):
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Demonstrates the pH durability Unison stationary phase series (UK-C18, UK-C8, UK-Phenyl)

Application #:
TI0117
Type:
Application Note
Categories:
Phase Interaction
Compounds:
caffeine
phenol
butylbenzene
amylbenzene
o-terphenyl. triphenylene
Column(s):
Cadenza CD-C18 (0 x 0mm)
Unison UK-C18 (0 x 0mm)

Differences in ODS stationary phase interactions between Unison and Cadenza.

Application #:
TI0115
Type:
Application Note
Categories:
Column Performance
Biochemistry / Metabolism
Compounds:
Theophylline
phenol
caffeine
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)

Retention properties of polar compounds

Application #:
TI0114
Type:
Application Note
Categories:
Retention Behavior on Unison and Cadenza
Compounds:
caffeine
butylparaben
diphenyl
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)

Comparison of elution quality between our high polar affinity ODS Unison column and high resolution Cadenza Column.

Application #:
TI0109
Type:
Application Note
Categories:
Organic Acids
Compounds:
formic acid
malonic acid
lactic acid
acetic acid
maleic acid
citric acid
succinic acid
fumaric acid
Column(s):
Unison UK-C18 (250 x 4.6mm)
Unison US-C18 (250 x 4.6mm)
Unison UK-C8 (250 x 4.6mm)
Unison UK-Phenyl (250 x 4.6mm)

Comparative separation of organic acids with various stationary phases of the Unison series.

Application #:
TI0107
Type:
Application Note
Categories:
Acrylamide
Compounds:
acrylamide
Column(s):
Unison UK-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 4.6mm)
Unison UK-C8 (250 x 4.6mm)
Unison UK-Phenyl (250 x 4.6mm)

Comparative retention of the highly polar compound acrylamide in the Unison series using 100% aqueous mobile phase.

Application #:
TI0106
Type:
Application Note
Categories:
Oligonucleotides
Compounds:
d(T)12-18
Column(s):
Cadenza CD-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)

Comparative elution between stationary phases in ammonium acetate.

Application #:
TI0103
Type:
Application Note
Categories:
Peptides
Tryptic Digest of alpha-Casein
Compounds:
alpha-Casein
tryptic digest
Column(s):
Unison UK-C18 (250 x 1.0mm)

Highly sensitive analysis using our 3um column with 1mm internal diameter.

Application #:
TI0102
Type:
Application Note
Categories:
Peptides
Tryptic Digest of alpha-Casein
Compounds:
alpha-Casein
tryptic digest
Column(s):
Unison UK-C18 (75 x 1.0mm)

High-speed analysis using our 3um column with 1mm internal diameter.

Application #:
TI0101
Type:
Application Note
Categories:
Peptides
Tryptic Digest of alpha-Casein
Compounds:
alpha-Casein
tryptic
Column(s):
Unison UK-C18 (250 x 2.0mm)

High resolution analysis using 250x2.0mm UK-C18.

Application #:
TI0100
Type:
Application Note
Categories:
Peptides
Tryptic Digest of alpha-Casein
Compounds:
alpha-Casein
tryptic digest
Column(s):
Unison UK-C18 (50 x 2.0mm)

High-speed analysis using our 50x2.0mm UK-C18.

Application #:
TI0088
Type:
Application Note
Categories:
Column performance in an aqueous elution
Compounds:
cytosine
uracil
cytidine,
Column(s):
Unison UK-C18 (30 x 4.6mm)
Unison UK-C18 (50 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C18 (100 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)
Unison UK-C18 (250 x 4.6mm)

Unison offers high performance in 100 percent aqueous elution, where conventional ODS columns lose retention.

Application #:
TI0083
Type:
Application Note
Categories:
Amino Acids-3
Compounds:
L-phenylalanine
L-isoleucine
L-lysine
L-tyrosine
L-histidine
L-proline
3,4--dihydroxy L-phenylalanine
L-methionine
L-ornithine
L-arginine
L-leucine
L-tryptophan
Column(s):
Unison UK-C18 (250 x 4.6mm)

Retention of underivitized amino acids by ODS column.

Application #:
TI0082
Type:
Application Note
Categories:
Amino Acids-2
Compounds:
L-threonine
L-alanine
L-cysteine
L-cystine
L-glutamic acid
L-valine
Column(s):
Unison UK-C18 (250 x 4.6mm)

Retention of underivitized amino acids by ODS column.

Application #:
TI0081
Type:
Application Note
Categories:
Amino Acids-1
Compounds:
L-aspartic acid
glycine
L-asparagine
L-serine
L-hydroxyproline
L-glutamine
Column(s):
Unison UK-C18 (250 x 4.6mm)

Retention of underivitized amino acids by ODS column.

Application #:
TI0079
Type:
Application Note
Categories:
Allergy Medications
Compounds:
tranilast
epinastine
chlorpheniramine
malate
diphenhydramine,
Column(s):
Unison UK-C18 (75 x 4.6mm)

High-speed analysis of basic anti-allergy medications with 3um UK-C18 column at neutral pH

Application #:
SP0040
Type:
Poster
Categories:
Column Performance
Compounds:
Column(s):
Intrada Amino Acid (0 x 0.0mm)
Intrada WP-RP (0 x 0.0mm)
Scherzo SW-C18 (0 x 0.0mm)
Scherzo SM-C18 (0 x 0.0mm)
Scherzo SS-C18 (0 x 0.0mm)
Cadenza CD-C18 (0 x 0.0mm)
Cadenza CW-C18 (0 x 0.0mm)
Cadenza CL-C18 (0 x 0.0mm)
Cadenza HS-C18 (0 x 0.0mm)
Unison UK-C18 (0 x 0.0mm)
Unison UK-C8 (0 x 0.0mm)
Unison UK-Phenyl (0 x 0.0mm)
Unison UK-Silica (0 x 0.0mm)
Unison UK-Amino (0 x 0.0mm)
Presto FF-C18 (0 x 0.0mm)
Intrada SEC (0 x 0.0mm)
Dacapo DX-C18 (0 x 0.0mm)
Cadenza CX-C18 (0 x 0.0mm)

Imtakt Product Comparisons: Product Descriptions

Application #:
SP0038
Type:
Poster
Categories:
Column Performance
Industrial Chemical
Environmental and Agricultural
Compounds:
o-terphenyl
triphenylene
Column(s):
Unison UK-C18 (150 x 3.0mm)
Dacapo DX-C18 (150 x 3.0mm)
Cadenza CX-C18 (150 x 3.0mm)

Imtakt Product Comparisons: Steric Selectivity

Application #:
SP0037
Type:
Poster
Categories:
Column Performance
Food Chemistry
Industrial Chemical
Environmental and Agricultural
Compounds:
caffeine
phenol
amylbenzene
butylbenzene
triphenylene
o-terphenyl
Column(s):
Cadenza CD-C18 (0 x 0.0mm)
Cadenza CW-C18 (0 x 0.0mm)
Cadenza CL-C18 (0 x 0.0mm)
Unison UK-C18 (0 x 0.0mm)
Dacapo DX-C18 (0 x 0.0mm)
Cadenza CX-C18 (0 x 0.0mm)

Imtakt Product Comparisons: Basic Interactions

Application #:
SP0021
Type:
Poster
Categories:
0
Compounds:
0
Column(s):
Intrada Amino Acid (10 x 2.0mm)
Intrada Amino Acid (50 x 3.0mm)
Intrada Amino Acid (75 x 2.0mm)
Intrada Amino Acid (100 x 3.0mm)
Intrada Amino Acid (150 x 2.0mm)
Intrada Amino Acid (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)
Unison UK-C18 (250 x 4.6mm)
Unison UK-Amino (250 x 2.0mm)

The world's first specialty column for intact amino acid analysis via LC-MS

Application #:
SP0010
Type:
Poster
Categories:
0
Compounds:
0
Column(s):
Unison UK-C18 (50 x 1.0mm)

High throughput analysis of anion surfactant using ultra-high speek LC-MS/MS and 1mm inside diameter column

Application #:
SP0004
Type:
Poster
Categories:
0
Compounds:
0
Column(s):
Scherzo SM-C18 (30 x 3.0mm)
Scherzo SM-C18 (50 x 3.0mm)
Scherzo SM-C18 (75 x 4.6mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 4.6mm)
Scherzo SM-C18 (250 x 3.0mm)
Unison UK-C18 (30 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 4.6mm)

A development and application study for anion exchange + cation exchange + normal phase + reversed-phase multi-mode ODS column

Application #:
SP0001
Type:
Poster
Categories:
0
Compounds:
0
Column(s):
Cadenza CD-C18 (50 x 2.0mm)
Unison UK-C18 (50 x 2.0mm)

Evalutation of Column Retention with large injection volume for high sensitive and high throughput LC-MS/MS Quantitative Analysis

Application #:
JA0024
Type:
Paper
Categories:
0
Compounds:
0
Column(s):
Unison UK-C18 (250 x 4.6mm)

Anti-hepatitis C virus compounds obtained from Glycyrrhiza uralensis and other Glycyrrhiza species

Application #:
JA0023
Type:
Paper
Categories:
0
Compounds:
0
Column(s):
Unison UK-C18 (100 x 10.0mm)

Binding potential of (E)-[11C]ABP688 to metabotropic glutamate receptor subtype 5 is decreased by the inclusion of its 11C-labelled Z-isomer

Application #:
JA0010
Type:
Paper
Categories:
0
Compounds:
0
Column(s):
Unison UK-C18 (50 x 2.0mm)

Quantification of propranolol in rat plasma by LC-MS/MS using tramadol as an internal standard: Application to pharmacokinetic studies in TAA-induced liver fibrotic rats

Application #:
JA0002
Type:
Paper
Categories:
0
Compounds:
0
Column(s):
Unison UK-C18 (150 x 3.0mm)

Time-course measurements of drugs and metabolites transferred from fingertips after drug administration: usefulness of fingerprints for drug testing

Application #:
JA0001
Type:
Paper
Categories:
0
Compounds:
0
Column(s):
Unison UK-C18 (30 x 2.0mm)
Unison UK-C8 (30 x 2.0mm)
Presto FF-C18 (30 x 2.0mm)

Universal LC–MS method for minimized carryover in a discovery bioanalytical setting

About Imtakt

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