Most aminopropyl columns have a fatal flaw: "column bleeding", or the rapid deterioration in retention as a result of ligand desorption under aqueous elution. Our newly-designed Unison UK-Amino offers a different approach from conventional columns: high durability against aqueous eluent.
Unison UK-Amino can conduct aqueous normal phase separation even with chemical compounds other than carbohydrates. The column can optimally handle various compounds with its combination of normal phase and anion exchange mode. Using LC-UV/VIS, LC-ELSD or LC-MS is possible by optimizing the eluent organic strength, buffer pH and ionic strength. |